LightScanner　HRM
－高分辨熔解曲线突变检测系统

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　　　　　　- Dr. Claire Taylor, University of Leeds, UK
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已具有详细Protocol的利用LightScanner进行突变扫描和基因分型的基因列表（不断更新中......）
利用LightScanner高分辨熔解曲线分析系统扫描过的基因已经超过1000个，我公司对下列列表中的基因为LightScanner用户提供详细的引物及探针的序列和分析方法（包括PCR条件等），请与我公司技术人员联系。

•  Cancer
•  Cardiac
•  Drug Metabolizing Enzymes - Transporters
•  Flavin Containing Monooxygenases
•  Glutathione-S-Transferases
•  Hemostasis
•  Metabolism
•  Neuronal
•  Solute Carrier Family  

METABOLISM

Assay Gene Assay Type Mutation

CETP

CHOLESTERYL ESTER TRANSFER PROTEIN, PLASMA

Whole gene analysis

N/A

LIPC

LIPASE, HEPATIC

Whole gene analysis

N/A

LPL

LIPOPROTEIN LIPASE

Whole gene analysis

N/A

LCAT

LECITHIN:CHOLESTEROL ACYLTRANSFERASE

Whole gene analysis

N/A

SCARB1

SCAVENGER RECEPTOR CLASS B, MEMBER 1

Whole gene analysis

N/A

ApoF

APOLIPOPROTEIN F

Whole gene analysis

N/A

MCAD

ACYL-CoA DEHYDROGENASE, MEDIUM-CHAIN

LunaProbe Genotyping Assay

985 A >G

MCAD

ACYL-CoA DEHYDROGENASE, MEDIUM-CHAIN

LunaProbe Genotyping Assay

199 T>C

MCAD

ACYL-CoA DEHYDROGENASE, MEDIUM-CHAIN

Whole gene analysis

N/A

OTC

ORNITHINE CARBAMOYLTRANSFERASE

Whole gene analysis

N/A

NAGS

N-ACETYLGLUTAMATE SYNTHASE

Whole gene analysis

N/A

GALT

GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE

Whole gene analysis

N/A

MTHFR

5,10-METHYLENETETRAHYDROFOLATE REDUCTASE

LunaProbe Genotyping Assay

A222V ( 677C >T)

MTHFR

5,10-METHYLENETETRAHYDROFOLATE REDUCTASE

LunaProbe Genotyping Assay

E 429A ( 1298A >C)

HFE

HEMOCHROMATOSIS

LunaProbe Genotyping Assay

H63D ( 187C >G)

HFE

HEMOCHROMATOSIS

LunaProbe Genotyping Assay

C282Y ( 845G >A)

HEMOSTASIS

Assay Gene Assay Type Mutation

A1AT

ALPHA-1-ANTITRYPSIN PROTEASE INHIBITOR

Whole gene analysis

N/A

Factor V

COAGULATION FACTOR V

LunaProbe Genotyping Assay

R506Q ( 1691G >A)

Prothrombin

COAGULATION FACTOR II

LunaProbe Genotyping Assay

20210 G >A

CFHx9

COMPLEMENT FACTOR H

Scanning

T/C Y402H, T 1277C poly

NEURONAL
Assay Gene Assay Type Mutation

SOD1x1

SUPEROXIDE DISMUTASE 1

Inquire

N/A

SMNx7

SURVIVAL OF MOTOR NEURON 1 (mouse)

Inquire

N/A

SOX1x1

SRY-BOX 1 (3 fragments)

Scanning

N/A

SPG4x9

SPASTIN (microtubule disassembly)

Scanning

N/A

HTR 2A

SEROTONIN RECEPTOR

Scanning x1

102 T>C

BMPR2

BONE MORPHOGENETIC PROTEIN RECEPTOR, TYPE II

Whole gene analysis

N/A

CARDIAC

Assay Gene Assay Type Mutation

MYH7x3

MYOSIN, HEAVY CHAIN 7, CARDIAC MUSCLE, BETA

Scanning

N/A

MYH7x12

MYOSIN, HEAVY CHAIN 7, CARDIAC MUSCLE, BETA

Scanning

N/A

MYBPC3x3

MYOSIN-BINDING PROTEIN C, CARDIAC

Scanning

N/A

MYBPC3x4

MYOSIN-BINDING PROTEIN C, CARDIAC

Scanning

N/A

MYBPC3x6

MYOSIN-BINDING PROTEIN C, CARDIAC

Scanning

N/A

TNNT2x3,4

TROPONIN T2, CARDIAC (thin filaments, single fragment)

Scanning

N/A

TNNI3x7

TROPONIN I, CARDIAC (thin filaments)

Scanning

N/A

TNNI3x8

TROPONIN I, CARDIAC (thin filaments)

Scanning

N/A

DRUG METABOLIZING ENZYMES/TRANSPORTERS

Assay Gene Assay Type Mutation

CYP1B1x2

Cytochrome P450, family 1, subfamily B, polypeptide 1

Scanning

N/A

CYP1B1x3

Cytochrome P450, family 1, subfamily B, polypeptide 1

Scanning

N/A

CYP2D6*6B

Cytochrome P450, family 2, subfamily D, polypeptide 6

LunaProbe Genotyping Assay

1707 T> DEL

CYP2D6* 4A

Cytochrome P450, family 2, subfamily D, polypeptide 6

LunaProbe Genotyping Assay

1846 G >A

CYP2D6*2xN/
*35xN

Cytochrome P450, family 2, subfamily D, polypeptide 6

LunaProbe Genotyping Assay

2850 C >T

CYP2D6*3

Cytochrome P450, family 2, subfamily D, polypeptide 6

LunaProbe Genotyping Assay

2549 A > del

CYP 2C 19*2

Cytochrome P450, family 2, subfamily C, polypeptide 19

LunaProbe Genotyping Assay

+ 19154 G >A

CYP 2C 19*3

Cytochrome P450, family 2, subfamily C, polypeptide 19

LunaProbe Genotyping Assay

+ 17948 G >A

CFTRx10

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (ABCC7)

Scanning

F508del, F 508C , I507del, I506V

CFTRx10

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (ABCC7)

LunaProbe Genotyping Assay

F508del, F 508C , I507del, I506V

CFTRx11

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (ABCC7)

LunaProbe Genotyping Assay

G542X

ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

LunaProbe Genotyping Assay

-129 T>C

ABCC2

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

LunaProbe Genotyping Assay

V417I
( 1249 G >T)

ABCC2

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

LunaProbe Genotyping Assay

C1515Y
( 4544 G >A)

ABCC2

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

LunaProbe Genotyping Assay

V1188E

ABCC3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

LunaProbe Genotyping Assay

R1297H

ABCG2

ATP-binding cassette, sub-family G (WHITE), member 2

LunaProbe Genotyping Assay

Q141K

SOLUTE CARRIER FAMILY

Assay Gene Assay Type Mutation

SLC 22A 1

Solute carrier family 22 (organic cation transporter), member 1

LunaProbe Genotyping Assay

G465R
( 32870 G > A)

SLC 22A 1

Solute carrier family 22 (organic cation transporter), member 1

LunaProbe Genotyping Assay

R 61C
( 286 C >T)

SLC 22A 1

Solute carrier family 22 (organic cation transporter), member 1

LunaProbe Genotyping Assay

L 160F
( 585 G >C)

SLC 22A 2

Solute carrier family 22 (organic cation transporter), member 2

LunaProbe Genotyping Assay

S 270A
(978 T>G)

SLCO1B1

Solute carrier organic anion transporter family, member 1B1

LunaProbe Genotyping Assay

N130D
( 484 A >G)

SLCO1B1

Solute carrier organic anion transporter family, member 1B1

LunaProbe Genotyping Assay

L 643F
( 2063 A >C)

SLCO1B1

Solute carrier organic anion transporter family, member 1B1

LunaProbe Genotyping Assay

V 174A
(617 T>C)

SLCO2B1

Solute carrier organic anion transporter family, member 2B1

LunaProbe Genotyping Assay

S 486F
( 1721 C >T)

SLCO2B1

Solute carrier organic anion transporter family, member 2B1

LunaProbe Genotyping Assay

V 210M
( 865 G >A)

SLCO2B1

Solute carrier organic anion transporter family, member 2B1

LunaProbe Genotyping Assay

Q312R
( 1199 A >G)

SLC 22A 1

Solute carrier family 22 (organic cation transporter), member 1

LunaProbe Genotyping Assay

G465R
( 32870 G > A)

SLC 22A 5

Solute carrier family 22, member 5

Whole gene analysis

N/A

FLAVIN CONTAINING MONOOXYGENASES

Assay Gene Assay Type Mutation

FMO3

Flavin containing monooxygenase 3

LunaProbe Genotyping Assay

E 308G
( 21443 A >G)

FMO3

Flavin containing monooxygenase 3

LunaProbe Genotyping Assay

E158K ( 15167G >A)

FMO3

Flavin containing monooxygenase 3

LunaProbe Genotyping Assay

V 257M
( 18281 G >A)

GLUTATHIONE-S-TRANSFERASES

Assay Gene Assay Type Mutation

GSTA2

Glutathione S-transferase A2

LunaProbe
Genotyping Assay

S112T
( 448 G >C)

GSTA2

Glutathione S-transferase A2

LunaProbe
Genotyping Assay

P110S
( 441 C >T)

GSTA2

Glutathione S-transferase A2

LunaProbe Genotyping Assay

E 210A
( 742 A >C)

GSTM3

Glutathione S-transferase M3 (brain)

LunaProbe
Genotyping Assay

V224I
( 801 G >A)

GSTP

Glutathione S-transferase pi

LunaProbe
Genotyping Assay

A114V
( 370 C >T)

CANCER

Assay Gene Assay Type Mutation

AXLx5

AXL RECEPTOR TYROSINE KINASE

Scanning

N/A

BRIP1

BRCA1-INTERACTING PROTEIN 1

Scanning

N/A

BRAFx11

V-RAF MURINE SARCOMA VIRAL ONCOGENE HOMOLOG B1

Scanning

N/A

BRAFx15

V-RAF MURINE SARCOMA VIRAL ONCOGENE HOMOLOG B1

Scanning

N/A

EGFRx18

EPIDERMAL GROWTH FACTOR RECEPTOR

Scanning

N/A

EGFRx19

EPIDERMAL GROWTH FACTOR RECEPTOR

Scanning

N/A

EGFRx20

EPIDERMAL GROWTH FACTOR RECEPTOR

Scanning

N/A

EGFRx20

EPIDERMAL GROWTH FACTOR RECEPTOR

LunaProbe Genotyping Assay

2361 G >A

EGFRx21

EPIDERMAL GROWTH FACTOR RECEPTOR

Scanning

N/A

ERBB2x23

V-ERB-B2 AVIAN ERYTHROBLASTIC LEUKEMIA VIRAL ONCOGENE HOMOLOG 2

Scanning

N/A

ERBB2x24

V-ERB-B2 AVIAN ERYTHROBLASTIC LEUKEMIA VIRAL ONCOGENE HOMOLOG 2

Scanning

N/A

FGF3Rx6

FIBROBLAST GROWTH FACTOR RECEPTOR 3

Scanning

N/A

FGF3Rx8

FIBROBLAST GROWTH FACTOR RECEPTOR 3

Scanning

N/A

FGF3Rx13

FIBROBLAST GROWTH FACTOR RECEPTOR 3

Scanning

N/A

FGF3Rx17

FIBROBLAST GROWTH FACTOR RECEPTOR 3

Scanning

N/A

Irf4

INTERFERON REGULATORY FACTOR 1

Scanning

N/A

JAK1x13

JANUS KINASE 1

Scanning

N/A

JAK2x14

JANUS KINASE 2

Scanning

N/A

JAK2x22

JANUS KINASE 2

Scanning

N/A

KITx2

V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG

Scanning

N/A

KITx8

V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG

Scanning

N/A

KITx9

V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG

Scanning

N/A

KITx11

V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG

Scanning

N/A

KITx12/13

V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG

Scanning

N/A

KITx15

V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG

Scanning

N/A

KITx17

V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG

Scanning

N/A

MSH2

MutL, E. COLI, HOMOLOG OF, 2

Whole gene analysis

N/A

MLH1

MutL, E. COLI, HOMOLOG OF, 1

Whole gene analysis

N/A

METx14

MET PROTOONCOGENE

Scanning

N/A

METx16

MET PROTOONCOGENE

Scanning

N/A

METx17

MET PROTOONCOGENE

Scanning

N/A

METx18

MET PROTOONCOGENE

Scanning

N/A

METx19

MET PROTOONCOGENE

Scanning

N/A

PDGFRAx10

PLATELET-DERIVED GROWTH FACTOR RECEPTOR, ALPHA

Scanning

N/A

PDGFRAx12

PLATELET-DERIVED GROWTH FACTOR RECEPTOR, ALPHA

Scanning

N/A

PDGFRAx18

PLATELET-DERIVED GROWTH FACTOR RECEPTOR, ALPHA

Scanning

N/A

PDPK1x3

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x4

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x5

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x6

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x7

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x8

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x9

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x10

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x11

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x12

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x13

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PDPK1x14

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1

Scanning

N/A

PIK3Cax2

PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, ALPHA

Scanning

N/A

PIK3Cax3

PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, ALPHA

Scanning

N/A

PIK3Cax5

PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, ALPHA

Scanning

N/A

PIK3Cax8

PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, ALPHA

Scanning

N/A

PIK3Cax10

PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, ALPHA

Scanning

N/A

PIK3Cax14

PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, ALPHA

Scanning

N/A

PIK3Cax19

PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, ALPHA

Scanning

N/A

PIK3Cax21

PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, ALPHA

Scanning

N/A

ROS1

V-ROS AVIAN UR2 SARCOMA VIRUS ONCOGENE HOMOLOG 1

Scanning

N/A

RETx10

REARRANGED DURING TRANSFECTION PROTOONCOGENE

Scanning

N/A

RETx16

REARRANGED DURING TRANSFECTION PROTOONCOGENE

Scanning

N/A

K-Rasx2

V-KI-RAS KIRSTEN RAT SARCOMA VIRAL ONCOGENE

Scanning

N/A

K-Rasx3

V-KI-RAS KIRSTEN RAT SARCOMA VIRAL ONCOGENE

Scanning

N/A

TP53x5

TUMOR PROTEIN p53

Scanning

N/A

 
   
   
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在线Presentation
高分辨熔点曲线，高分辨溶点曲线, 高分辨溶解曲线突变检测 ，高分辨溶解曲线分析系统，高分辨熔解曲线分析系统，高分辨融解曲线分析，突变检测 ，高分辨率熔解曲线分析 ，高分辨率融解曲线，高分辨率溶解曲线，高分辨率熔解曲线
 
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